36. The poet Yeats wrote: An aged man is but a paltry thing, A tattered cloak upon a stick, unless... A. He finds a younger woman, has a fling, And then yells out, "I never will confess!". B. He takes Viagra pills, to boldly bring To his beloved his mighty manliness. C. He uses Rogaine, and by next spring Has hair regrowth that's certain to impress. * D. Soul clap its hands and sing, and louder sing For every tatter in its mortal dress. E. He burns his "Path" book, and while it's smoldering, He shouts out loud, "I'm DONE with that B.S.!" 37. Papillary growth pattern in a cancer tell you it's probably * A. adenocarcinoma or transitional cell carcinoma B. leukemia or lymphoma C. melanoma D. sarcoma E. squamous cell carcinoma 38. What is the common FATAL cancer in US men? A. bladder B. colon C. leukemia * D. lung E. prostate 39. "Rhabdo" tumors derive from A. blood elements B. nerve elements * C. skeletal muscle D. smooth muscle E. squamous epithelium 40. The pathologist stained the slide with Ki-67 immunostain, wishing to know... A. if this was of mesenchymal origin B. if this was a metastasis C. if this was adenocarcinoma D. if this was squamous carcinoma * E. what percent of cells were dividing 41. Cathepsin B produced by cancer cells lets them A. adhere to endothelium B. avoid undergoing apoptosis C. evade immune surveillance D. induce blood vessel ingrowth * E. penetrate basement membranes 42. Blocking either this or its receptor has slowed down cancer spread very impressively in recent work. A. basic fibroblast growth factor B. cadherin C. interleukin 8 D. ras GTPase * E. vascular endothelial growth factor 43. Whose test for mutagenicity uses typhoid bacilli? * A. Ames B. Delaney C. Pindborg D. Warberg E. Zumwaldt 44. Fern-shaped marks on the skin of a dead body found outside suggest... A. cockroaches B. freezing (ice crystals) * C. lightning D. maggots on the inside E. rats 45. Your chronic lymphocytic leukemia patients will get tested (hopefully by you) for translocation activation of this gene to form the Philadelphia chromosome. * A. abl B. myc C. p53 D. ras E. src 46. Hyponatremia from excessive antidiuretic hormone production will make you think of A. adenocarcinoma of the lung B. colon cancer * C. oat cell (small cell) lung cancer D. pituitary adenoma E. squamous lung cancer 47. US men from which genetic group have the highest risk for prostate cancer? * A. African-American B. Chinese / Vietnamese C. East Indian D. Native American (First American) E. Northern European, non-Jewish 48. Uncle Sam began adding lots of this to the food last January. * A. folic acid B. vitamin A C. vitamin C D. vitamin D E. vitamin E 49. Which vitamin is deficient enough in some children with cystic fibrosis to cause hemolysis? A. A B. B1 C. C * D. E E. folic acid 50. Increased intracranial pressure? Perhaps the patient is taking too much... * A. vitamin A B. vitamin B1 C. vitamin C D. vitamin D E. vitamin E 51. You'll see the LEAST fibrosis in A. asbestosis B. berylliosis * C. emphysema from smoking D. farmer's lung with longstanding vasculitis E. silicosis 52. The guy who snorted Ajax cleanser got A. asbestosis B. asthma C. berylliosis * D. silicosis E. tuberculosis 53. NOT a component of farmer's lung * A. antibody-mediated cytotoxicity (type II injury) B. T-cell mediated havoc C. vasculitis from antigen-antibody complexes D. wheezing from histamine release E. wheezing from leukotriene release 54. Big doses will give you non-immune hemolysis... A. erythromycin B. bleomycin * C. penicillin D. phenytoin E. zinc protoporphyrin 55. Crusty lesions on the palms suggest toxicity from A. antimony * B. arsenic C. lead D. mercury E. paraquat 56. Caffeine use clearly places its users at increased risk for A. bladder cancer B. high blood pressure C. pancreatic cancer D. sudden death * E. worse "hypoglycemia" symptoms 57. Rubbing alcohol, ingested by "rubby dubs", is A. ethyl alcohol B. methyl alcohol * C. isopropyl alcohol D. tert-butyl alcohol E. none of these 58. Bullet A is travelling twice as fast as bullet B. Both weigh the same. Bullet A carries how much more tissue- damaging energy than bullet B? A. sixteen B. eight * C. four D. two E. 1.414 (the square root of two) 59. "Cigar bodies" are the tissue form of which micro-organism? A. amoebic dysentery organism B. anthrax spores C. nocardia * D. sporotrichosis fungus E. tetanus spores 60. Virulent meningococci are adept at destroying A. complement B. endothelium * C. IgA D. IgG E. IgM 61. Katayama fever is caused by A. gram-negative bacteria B. gram-positive bacteria C. protozoans D. rickettsia * E. schistosomes 62. You smell bitter almonds when you open the body. He probably died of... A. arsenic B. banana split intoxication * C. cyanide D. lead poisoning E. mercury 63. "Very low birth weight" is less than how many grams? A. 500 B. 1000 * C. 1500 D. 2000 E. 2500 64. What micro-organism, in health, is taken up by the CFTR receptor for intracellular destruction? A. cholera bacillus B. proteus * C. pseudomonas D. TB bacillus E. typhoid bacillus 65. The telomeres vanish rapidly in... * A. ataxia-telangiectasia B. Bloom's syndrome C. Hutchinson-Gilford progeria D. tuberous sclerosis E. Werner's disease 66. Endothelin? A. binds von Willebrand's factor * B. constricts small vessels C. dilates small vessels D. growth factor for streptococci E. receptor for rickettsia 67. Which is NOT a cause of hyperplastic arteriolar sclerosis? A. hemolytic-uremic syndrome ("Jack in the Box") B. scleroderma C. severe pulmonary high blood pressure D. severe systemic high blood pressure * E. small-vessel polyarteritis nodosa 68. Which is NOT a defining characteristic of Kawasaki's? * A. anemia B. cervical lymphadenopathy C. fever D. mouth lesions E. red palms and soles 69. Fatty streaks usually begin when? * A. infancy B. childhood C. adolescence D. midlife crisis E. most people never get them 70. In the US during this century, most lymphangiosarcomas have been A. caused by smoking B. childhood tumors * C. iatrogenic D. radiation-induced E. successfully resected for cure 71, TWO KODACHROMES. Which type of leprosy? * A. lepromatous / multibacillary B. tuberculoid / paucibacillary 72, ONE KODACHROME. What killed him? A. beating B. drowning * C. gunshot wound D. strangled (conjunctival petechiae) E. thermal burn 73. ONE KODACHROME. Which deficiency disease? A. kwashiorkor * B. marasmus C. rickets D. scurvy E. vitamin A deficiency 74. ONE KODACHROME. Changes of A. anthrax * B. decomposition C. leprosy D. thermal burn E. syphilis 75, ONE KODACHROME. The etiologic agent is * A. DNA virus B. fungus C. gram positive bacterium D. gram negative bacterium E. RNA virus 76. THREE KODACHROMES. CNS infection. What's the agent? * A. aspergillus B. candida C. cryptococcus D. mucormycosis E. toxoplasmosis 77. TWO KODACHROMES. Blood vessels. Lesions of A. atherosclerosis B. medial calcific sclerosis * C. high blood pressure D. polyarteritis nodosa E. syphilis 78. What is the most likely bug? A. fungus B. rickettsia C. spirochete * D. staphylococcus E. streptococcus 79. ONE KODACHROME. Cervix. What's the diagnosis? A. adenocarcinoma B. candida C. gonorrhea or some other bacterial infection * D. herpes E. squamous cancer 80. ONE KODACHROME. What fungus? A. aspergillus * B. blastomyces C. candida D. cryptococcus E. mucormycosis 81. TWO KODACHROMES. Morphology of the etiologic agent? A. gram negative coccus B. gram negative rod C. gram positive coccus * D. gram positive rod E. none of these, it is a virus 82. TWO KODACHROMES. Autoerotic asphyxia. Where should we look for those famous Tardieu spots? A. conjunctiva B. epiglottis * C. legs D. genitals and rectum E. oral mucosa 83. TWO KODACHROMES. Mostly what kind of injuries? * A. abrasions B. gunshot wounds C. incised wounds D. lacerations E. thermal burns 84. ONE KODACHROME. What class of micro-organism? * A. gram-positive rod B. gram-negative rod C. fungus D. mycobacterium E. virus 85. ONE KODACHROME. What kind of wound? * A. incision B. laceration C. shotgun wound D. thermal burn E. traumatic asphyxiation 86. TWO KODACHROMES. Lung. A. adenocarcinoma B. candida C. cryptococcus D. histoplasmosis * E. pneumocystis 87. ONE KODACHROME. Pap smear. * A. cancer B. candida C. gonorrhea D. trichomonas E. wart 88. ONE KODACHROME. What fungus? A. candida * B. coccidioidomycosis C. cryptococcus D. histoplasmosis E. South American blastomycosis 89. ONE KODACHROME. Prostate. What's the diagnosis? A. acute inflammation, consistent with bacteria * B. adenocarcinoma C. spindle cell sarcoma D. squamous cell carcinoma E. telangiectasia or hemangioma 90. ONE KODACHROME. Pancreas. What's the diagnosis? A. adenocarcinoma B. cystic fibrosis * C. cytomegalovirus D. healing following trauma E. this is normal pancreas 91. TWO KODACHROMES. Your best diagnosis? * A. leprosy B. neurofibromatosis C. rocky mountain spotted fever D. tinea versicolor E. xeroderma pigmentosum 92. TWO KODACHROMES. What fungus? A. blastomycosis B. candida C. coccidioidomycosis D. cryptococcus * E. histoplasmosis 93. ONE KODACHROME. Most likely microbe? A. herpes B. meningococcal sepsis or rickettsia C. pseudomonas ecthyma gangrenosum D. staphylococcus * E. streptococcus 94. ONE KODACHROME. What kind of injury? A. abrasion B. gunshot C. incised wound * D. laceration E. shotgun 95. TWO KODACHROMES. Diphtheria causes fatty change by tying up A. glycolysis B. ketoacid synthesis C. oxidative phosphorylation D. synthesis of lipoproteins * E. the carnitine shuttle 96. ONE KODACHROME. What kind of wound? * A. close-contact gunshot B. gunshot exit C. midrange gunshot (powder stippling) D. laceration not caused by a gun E. long-range gunshot 97. ONE KODACHROME. Which deficiency disease? * A. kwashiorkor B. pellagra C. rickets D. scurvy E. this is congenital syphilis 98. ONE KODACHROME. Which fungus infection? A. actinomycosis, not really a fungus B. blastomycosis, was on the riverbank C. candida, consider underlying immunosuppression D. histoplasmosis, bad case even for Kansas City * E. sporotrichosis, a gardener 99. ONE KODACHROME. Five year old boy. Which type of progeria? A. Ataxia-Telangiectasia B. Ehlers-Danlos * C. Hutchinson-Gilford classic D. Werner's E. Xeroderma pigmentosum 100. ONE KODACHROME. Matt was playing chicken on the train tracks. Somebody dared him. Assuming these facts are correct, what is the MANNER of death? * A. accident B. homicide C. natural D. suicide E. undetermined BONUS ITEMS. One point each. 101. TWO KODACHROMES. Lung, Diagnosis, please. [actinomycosis] 102. THREE KODACHROMES. Skin lesion. Must be... [melanoma] 103. ONE KODACHROME. "Hand foot and mouth disease." Which virus causes it? [coxsackie] 104. ONE KODACHROME. Coronary artery. What are those white needle things? [cholesterol] 105. ONE KODACHROME. Which species of schistosome laid this egg? [mansoni] 106. THREE KODACHROMES. Skin lesions. What is the diagnosis? [syphilis] 107. TWO KODACHROMES. Two suicides who both selected what kind of firearm? [shotgun] 108. ONE KODACHROME. What's the special name we give to these incised wounds? [defensive] 109. ONE KODACHROME. Retina. What cancer syndrome? [von Hippel-Lindau] 110. TWO KODACHROMES. Skin lesion. What's your diagnosis? [any herpes] 111. TWO KODACHROMES. Skin trouble. Your best diagnosis? [syphilis] 112. ONE KODACHROME. Which fungus? [paracoccidioides / S.A. blasto] 113. ONE KODACHROME. Manner of death, and how you know. Be specific. [manual strangulation, marks on neck] 114. THREE KODACHROMES. Your best diagnosis. Please be specific. [squamous cell carcinoma] 115. TWO KODACHROMES. Man trouble. Your diagnosis. [gonorrhea] 116. ONE KODACHROME. Somewhere in the GI tract. Your best diagnosis? [cryptosporidiosis, accept isosporidiosis] 117. ONE KODACHROME. Identify me. Be specific. [louse] 118. ONE KODACHROME. Heart. Your best diagnosis? [accept any cancer diagnosis] 119. ONE KODACHROME. Shotgun suicide. What do we call the contraction of muscles that's holding this fellow's arms in place? [rigor mortis] 120. ONE KODACHROME. Why is this man smiling? [did not land on knives in dishwasher; +1 for any good answer.]