31. Which is NOT caused by parvo B19? (A) arthritis / joint pain (B) bone marrow failure in sickle cell disease (C) erythema infectiosum (D) hydrops fetalis * (E) roseola infantum 32. Inclusion body conjunctivitis is caused by a (A) bacterium * (B) chlamydia (C) protozoan (D) rickettsia (E) virus 33. Which layer of the skin is affected by uncomplicated impetigo? (A) deeper epidermis only (B) dermis only (C) full thickness of epidermis * (D) stratum corneum only (E) subcutaneous fat 34. How is echovirus transmitted? (A) arthropods (arbovirus) (B) casual skin conctact in most cases (C) droplets (sneezing and coughing) * (D) fecal-oral (E) sex or IV drug use 35. Usually caught by eating undercooked meat (A) acanthamoebia (B) cryptosporidiosis (C) giardia (D) naegleria * (E) sarcocystis 36. A favorite trivia question for students on "Gastroenterology" is, "Where is the hepatic necrosis in yellow fever?" (A) around the bile ducts (B) centrilobular * (C) midzonal (D) periportal (E) portal vein radicles 37. In "insulin resistance syndrome", the distinctive lipoprotein pattern is (A) high LDL, normal HDL, high triglycerides (B) high LDL, high triglycerides (C) high LDL, high HDL * (D) low HDL, high triglycerides (E) high triglycerides only, with significant coronary risk 38. All predispose to atherosclerosis EXCEPT... (A) after coronary angioplasty (B) after mantle radiation for Hodgkin's (C) coronaries in a transplanted heart * (D) Monckeberg's medial calcific sclerosis (E) vein used as a coronary graft 39. The pigment around the ankles in folks with varicose veins is (A) carbon * (B) hemosiderin (C) lipofuscin (old people) (D) melanin (E) dye from tight-fitting shoes 40. What's the usual cuase of Trousseau's migratory thrombophlebitis? (A) bacterial infections such as Lyme disease (B) immune complex vasculitis (C) portal hypertension (D) mechanical injury to the valves * (E) remote effect of cancer 41. A young Asian-American man is found dead in his bed in the morning. All that had been noticed beforehand was a known right bundle branch block. What killed him? (A) Barlow's syndrome, bad form * (B) Brugada syndrome (C) Lutembacher's syndrome (D) Pickwickian syndrome (E) Syndrome X 42. Where are you going to look for those Roth spots? (A) buccal mucosa (B) extensor tendons (C) fingernails (D) finger pulp * (E) optic fundi 43. What will you see in a death from arrhythmogenic right ventricular dysplasia? (A) anaplasia without invasion (B) crisscrossing heart muscle cells (C) fatty change within the heart muscle cells * (D) fibrosis and fat cells between cardiac muscle cells (E) wavy fibers and thickened vascular intima 44. Prinzmetal's angina is due to (A) cocaine * (B) coronary spasm (C) developing thrombus (D) esophageal dysfunction (E) lack of autonomic tone 45. What's the most common primary tumor of the heart? (A) carcinoid (B) granular cell myoblastoma (C) lipoma * (D) myxoma (E) rhabdomyoma 46. Which is LEAST LIKELY to produce pulmonary fibrosis? (A) berylliosis * (B) lupus (C) rheumatoid arthritis (D) sarcoidosis (E) scleroderma 47. Nickel dust is a known risk factor for (A) bronchiectasis (B) emphysema (C) lung cancer (D) mesothelioma (E) occupational asthma 48. Neuron-specific enolase positivity is a good way to confirm that your lung cancer is (A) adenocarcinoma (B) squamous cell carcinoma * (C) oat cell carcinoma (D) mesothelioma (E) metastatic from the brain 49. Drinking paraquat will characteristically give you (A) bronchopneumonia (B) endogenous lipid pneumonia (C) exogenous lipid pneumonia * (D) pulmonary fibrosis (E) a nice high 50. Tonofilaments on electron microscopy confirm that your lung cancer is: (A) adenocarcinoma (B) large-cell * (C) squamous (D) oat cell (E) metastatic from the toe 51. In paroxysmal nocturnal hemoglobinuria, the red cells... (A) lyse due to blood pooling in the sacral area (B) lyse in the kidney, resulting in loss of hemoglobin (C) lyse in the absence of cortisol, due to its circadian rhythm * (D) lyse from enhanced sensitivity to complement at low pH (E) lyse from daily exercise, the hemoglobin being lost at night 52. Formaminoglutamic acid, when increased in the urine, suggests deficiency in (A) cell-mediated immunity * (B) folic acid (C) thiamine (D) vitamin C (E) psychic energy 53. Which antibiotic is infamous for occasionally suppressing erythropoiesis severely and permanently? (A) ampicillin (B) chloramphenicol (C) erythromycin ("erythro" means "red") (D) gentamicin (E) rifampin 54. ONE KODACHROME. Aorta and iliacs. The effects of * (A) atherosclerosis (B) dissecting "aneurysm" (C) syphilis (D) Takayasu's (E) trauma 55. ONE KODACHROME. Your best diagnosis: (A) capillary hemangioma (B) erysipelas (C) glomus tumor * (D) port-wine stain (E) rheumatic fever 56. ONE KODACHROME. Heart. Your best diagnosis? (A) acute myocardial infarct * (B) endocardial fibroelastosis (C) hypertrophic cardiomyopathy (D) rheumatic fever, acute (E) rheumatic fever, old 57. ONE KODACHROME. Coronary artery. Which is NOT present (A) calcium deposit (B) cholesterol needle * (C) fibrous cap (D) fresh thrombus (E) intact media 58. THREE KODACHROMES. Your best diagnosis? (A) angiosarcoma with hemorrhage (B) aortic dissection * (C) atherosclerotic aneurysm (D) blunt trauma with aortic laceration allow (E) syphilitic aneurysm 59. ONE KODACHROME. Give a reasonable age for this myocardial infarct. (A) 1 hour (B) 12 hours * (C) 4 days (D) 2 weeks (E) 1 year 60. ONE KODACHROME. What's wrong with the mitral valve? (A) acute rheumatic fever (B) bacterial endocarditis * (C) Barlow valve (D) ruptured papillary muscle (E) nothing 61. ONE KODACHROME. Lung. Your best diagnosis? (A) carcinoma consistent with oat cell (B) bronchiectasis * (C) pulmonary thromboembolus (D) tuberculosis or histoplasmosis (E) normal lung 62. ONE KODACHROME. What's with this lung? (A) adenocarcinoma, with acini (B) lipid pneumonia (C) squamous cell carcinoma (D) oat cell carcinoma * (E) none of these 63. ONE KODACHROME. Iatrogenic lung disease! Which one's the culprit! (A) amiodarona (B) busulfan ("Myleran") * (C) FenPhen (the obesity pill) (D) mineral oil (E) nitrofurantoin with eosinophils 64. ONE KODACHROME. What's this in the lung? (A) bronchiectasis (B) Chiari network (C) chronic bronchitis * (D) old pulmonary emboli (E) rheumatic fever 65. ONE KODACROME. This mesothelioma will give you... (A) obstructive disease * (B) restrictive disease 66. ONE KODACHROME. What lung cancer? * (A) adenocarcinoma (B) carcinoid (C) oat cell (D) squamous (E) uh, this is a granuloma 67. ONE KODACHROME. Liver mass! (A) adenocarcinoma from somewhere or other * (B) oat cell from the lung, most likely (C) squamous cell from somewhere or other (D) uh... this is chronic inflammation (E) uh... this is pyknotic nuclei from liver necrosis 68. TWO KODACHROMES. Diagnose this infectious disease. PAS and silver stains. (A) blastomycosis (B) candidiasis * (C) histoplasmosis (D) legionella (E) pneumocystosis 69. FOUR KODACHROMES. Diagnose this infectious disease. (A) acute rheumatic fever (B) bacterial endocarditis survivor * (C) leprosy (D) syphilis (E) tuberculosis 70. TWO KODACHROMES. What infection (A) cytomegalovirus (B) Kaposi "sarcoma" (C) molluscum contagiosum (D) rubella * (E) varicella 71. TWO KODACHROMES. What infection? (A) aspergillosis (B) blastomycosis (C) candidiasis (D) histoplasmosis * (E) pneumocystis 72. ONE KODACHROME. What infection? (A) erysipelas (B) herpes gladiatorum (C) impetigo (D) tinea versicolor * (E) zoster 73. TWO KODACHROMES. What infection? (A) histoplasmosis * (B) blastomycosis (C) coccidioides (D) cryptococcus (E) sporotrichosis 74. ONE KODACHROME. What infection? (A) candidiasis * (B) coccidioidomycosis (C) histoplasmosis (D) sporotrichosis (E) tuberculosis 75. THREE KODACHROMES. What infection? * (A) actinomycosis (B) candidiasis (C) impetigo (D) nocardiosis (E) staph infection with pus 76. ONE KODACHROME. Most likely infectious agnet? (A) anaerobe mixture (B) corynebacterium (C) diphtheria * (D) staphylococcus (E) streptococcus 77. ONE KODACHROME. What's wrong with the blood? * (A) abetalipoproteinemia (B) iron deficiency (C) malaria (D) sickle cell disease (E) target cells for some reason or other 78. ONE KODACHROME. What's wrong with the blood? * (A) hemolysis (B) iron deficiency (C) leukemia (D) megaloblastic anemia (E) thalassemia 79. ONE KODACHROME. What's wrong with the blood? (A) G6PD deficiency (B) hemoglobin E disease (C) leukemia * (D) pernicious anemia (E) thalassemia 80. ONE KODACHROME. What's wrong with the blood? (A) hemoglobin C disease (B) G6PD deficiency (C) malaria * (D) sickle cell anemia (E) thalassemia BONUS ITEMS 81. TWO KODACHROMES. What is the daignosis? [crab lice] 82. ONE KODACHROME. Heart. Your best diagnosis, please. [aneurysm after MI; "aneurysm" or "old MI" is fine] 83. ONE KODACHROME. Heart. Your best diagnosis, please. [carcinoma] 84. ONE KODACHROME. Tricuspid aortic valve stenosis WHy sudden death? [limited diastolic filling or bernoulli principle sucks blood from coronaries] 85. ONE KODACHROME. Autopsy "block" from the front. What is the diagnosis? [dextrocardia] 86. ONE KODACHROME. Plague year. What's a fomite? [inanimate carries germs] 87. ONE KODAHROME. Mitral valve. What is the diagnosis? [rheumatic valve] 88. TWO KODACHROMES. Lung. What's the daignosis? Be specific! [lung infarct] 89. What is a jet lesion? [on endocardium where jet of blood hits] 90. What's the common problem in all forms of thalassemia? [cannot make enough of a kind of globin chain] 91. What's a "glycation product"? [I need something about non-enzymatic addition of glucose to protein] 92. What is the predominant cell in the spleen in patients with typhoid? [macrophage / monocyte] 93. What's Fitz-Hugh-Curtis syndrome? [gonorrhea around the liver] 94. What's the main pre-existing risk factor for an anaerobic lung infection? [rotten teeth] 95. Why are these men smiling? [Christmas at the National Cathedral with my foster-son's brother, Jerry. Just recovering from TB at the time, explaining the weight loss. +1 for any correct answer.] NAME: _______________ Who's near you? UHS PATHOLOGY 1999-2000 Exam III Instructions: You know how to do this. Please don't phonate. GOOD LUCK!